PUBLICATIONS
2018
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE |
|---|---|---|---|---|---|
 | AD | Age dependency of risk factors for cognitive decline | BMC Geriatrics 2018 18:187 | Legdeur N, Heymans MW, Comijs HC, Huisman M, Maier AB, Visser PJ | 2018-07-01 |
| AD | The EMIF-AD PreclinAD study: Study Design and Baseline Cohort Overview | Alzheimers Res Ther. 2018 Aug 4;10(1):75 | Konijnenberg E, Carter SF, Ten Kate M, den Braber A, Tomassen J, Amadi C et al. | 2018-06-30 |
| AD | Capturing the Alzheimer’s disease pathological cascade | Lancet Neurol. 2018 Mar;17(3):199-200 | Tijms BM, Visser PJ | 2018-06-30 |
| AD | Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data | Front Aging Neurosci. 2018 Jun 25;10:193 | Bos I, Vos SJ, Jansen WJ, Vandenberghe R, Gabel S, Estanga A et al. | 2018-06-25 |
| AD | Inter-laboratory Proficiency Processing scheme in CSF aliquoting: Implementation and assessment based on biomarkers of Alzheimer’s Disease | Alzheimer's Research & Therapy201810:87 | Lewczuk P, Gaignaux A, Kofanova O, Ermann N, Betsou F, Brandner S et al. | 2018-08-28 |
| AD | The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics | Alzheimers Res Ther. 2018 Jul 6;10(1):64 | Bos I, Vos SJ, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni G et al. | 2018-07-06 |
| AD | MRI predictors of amyloid pathology: results from the EMIF-AD multimodal biomarker discovery study | Alzheimer's Research & Therapy201810:100 | Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R et al. | 2018-06-01 |
| AD | CSF non-phosphorylated Tau as a biomarker for the discrimination of AD from CJD | Ann Clin Transl Neurol. 2018 Jul; 5(7): 883–887 | Ermann N, Lewczuk P, Schimetz M, Lange P, Knipper T, Goebel S et al. | 2018-05-26 |
| AD | Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration | Alzheimers Res Ther. 2018 Mar 20;10(1):31 | Goossens J, Bjerke M, Van Mossevelde S, Van den Bossche T, Goeman J, De Vil B et al. | 2018-03-20 |
| AD | White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation | Alzheimers Res Ther. 2018 Mar 15;10(1):30 | Teunissen CE, Otto M, Engelborghs S, Herukka SK, Lehmann S, Lewczuk P et al. | 2018-03-15 |
| AD | Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study | Clin Chem. 2018 Jun;64(6):927-937 | Willemse EAJ, De Vos A, Herries EM, Andreasson U, Engelborghs S, van der Flier WM | 2018-03-01 |
| AD | Added Diagnostic Value of Cerebrospinal Fluid Biomarkers for Differential Dementia Diagnosis in an Autopsy-Confirmed Cohort | J Alzheimers Dis. 2018;63(1):373-381 | Niemantsverdriet E, Feyen BFE, Le Bastard N, Martin JJ, Goeman J, De Deyn PP, Bjerke M, Engelborghs S | 2018-02-02 |
| AD | Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue. | EBioMedicine. 2018 Apr;30:248-260 | Gao H, Kerr A, Jiao H, Hon CC, Rydén M, Dahlman I, Arner P | 2018-01-01 |
| AD | Gray matter network disruptions and amyloid beta in cognitively normal adults | Front Aging Neurosci. 2018 Mar 15;10:67 | Ten Kate M, Visser PJ, Bakardjian H, Barkhof F, Sikkes SAM, van der Flier WM et al. | 2018-01-01 |
| AD | Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease | Alzheimers Res Ther. 2018 Jul 28;10(1):71 | Lewczuk P, Ermann N, Andreasson U, Schultheis C, Podhorna J, Spitzer P et al. | 2018-07-28 |
| AD | Amyloid β oligomers (AβOs) in Alzheimer's disease | J Neural Transm (Vienna). 2018 Feb;125(2):177-191 | Mroczko B, Groblewska M, Litman-Zawadzka A, Kornhuber J, Lewczuk P | 2018-02-01 |
| AD | A Specific Reduction in Aβ1-42 vs. a Universal Loss of Aβ Peptides in CSF Differentiates Alzheimer's Disease from Meningitis and Multiple Sclerosis. | Front Aging Neurosci. 2018 May 24;10:152 | Spitzer P, Lang R, Oberstein TJ, Lewczuk P, Ermann N, Huttner HB, Masouris I, Kornhuber J, Ködel U, Maler JM | 2018-05-24 |
| AD | White matter hyperintensities and vascular risk factors in monozygotic twins | Neurobiol Aging. 2018 Jun;66:40-48 | Ten Kate M, Sudre CH, den Braber A, Konijnenberg E, Nivard MG, Cardoso MJ, Scheltens P, Ourselin S, Boomsma DI, Barkhof F, Visser PJ | 2018-06-01 |
| AD | Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia | JAMA Psychiatry. 2018 Jan 1;75(1):84-95 | Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE et al. | 2018-01-01 |
| AD | Screening of Potential Adipokines Identifies S100A4 as a Marker of Pernicious Adipose Tissue and Insulin Resistance | Int J Obes (Lond). 2018 Jan 30 | Arner P, Petrus P, Esteve D, Boulomié A, Näslund E, Thorell A et al. | 2018-01-30 |
| AD | Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry | World J Biol Psychiatry. 2018 Jun;19(4):244-328 | Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ et al. | 2018-06-01 |
| AD | Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource | Alzheimers Dement. 2018 Feb;14(2):130-139 | Perera G, Pedersen L, Ansel D, Alexander M, Arrighi HM, Avillach P et al. | 2018-02-01 |
| AD | Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer's Disease | Int J Mol Sci. 2018 Jun 27;19(7) | Mroczko B, Groblewska M, Litman-Zawadzka A, Kornhuber J, Lewczuk P | 2018-06-27 |
| AD | Amyloid production and aggregation in preclinical Alzheimer’s disease - a monozygotic twin study | Alzheimers Res Ther. 2018 Aug 4;10(1):75 | Konijnenberg E, Carter SF, Ten Kate M, den Braber A, Tomassen J, Amadi C et al. | 2018-08-04 |
| Metabolic | Gamma-glutamyltranspeptidase fractions in obese subjects with type 2 diabetes: relation to insulin sensitivity and effects of bariatric surgery | Obes Surg. 2018 May;28(5):1363-1371 | Franzini M, Musetti V, Guarino D, Caponi L, Paolicchi A, Emdin M, Ferrannini E, Nannipieri M. | 2018-05-28 |
| Metabolic | Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes. | EBioMedicine. 2018 Jan;27:151-155 | Mardinoglu A, Gogg S, Lotta LA, Stančáková A, Nerstedt A, Boren J et al. | 2018-01-01 |
| Metabolic | Systems biology in hepatology: approaches and applications. | Nat Rev Gastroenterol Hepatol. 2018 Jun;15(6):365-377 | Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J et al. | 2018-01-01 |
| Platform | Key Ethical Challenges in the European Medical Information Framework | Minds and Machines doi.org/10.1007/s11023-018-9467-4 | Foridi L, Luetge C, Pagallo U, Schefr B, Valcke P, Vayena E et al. | 2018-07-09 |
| Platform | MONTRA: An agile architecture for data publishing and discovery | Comput Methods Programs Biomed. 2018 Jul;160:33-42 | Silva LB, Trifan A, Oliveria JL | 2018-07-01 |
| Platform | A methodology for fine-grained access control in exposing biomedical data | Stud Health Technol Inform. 2018;247:561-565 | Trifan A, van der Lei J, Díaz C, Oliveira JL | 2018-09-01 |
| Platform | Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease | BMC Med. 2018; 16: 130 | Alexander M, Loomis K, Fairburn-Beech J, Van der Lei J, Duarte-Salles T, Prieto-Alhambra D et al. | 2018-02-28 |
| Platform | A modular workflow management framework | In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, 414-421, 2018 | Almeida JR, Ribeiro R, Oliveira JL | 2018-01-19 |
| Platform | A methodology to perform semi-automatic distributed EHR database queries | Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, 127-134, 2018 | Fajarda O, Silva LB, Rijnbeek PR, Van Speybroeck M, Oliveria JL | 2018-01-19 |
| Platform | A De-Identification Pipeline for Ultrasound Medical Images in DICOM Format. | J Med Syst. 2017 May;41(5):89. doi: 10.1007/s10916-017-0736-1 | Monteiro E, Costa C, Oliveria JL | 2018-05-01 |
| Platform | comoRbidity: An R package for the systematic analysis of disease comorbidities. | Bioinformatics 2018 Sep 15; 18:3228–3230 | Gutiérrez-Sacristán A, Bravo A, Giannoula A, Myaer MA, Sanz F, Furlong LI | 2018-04-20 |
| Platform | Identifying temporal patterns in patient disease trajectories using dynamic time warping: A population-based study | Sci Rep, 2018; 8(1): 4216 | Giannoula A, Gutierrez Sacristán A, Bravo A, Sanz F, Furlong LI | 2018-03-09 |
2017
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE | |
|---|---|---|---|---|---|---|
| Metabolic | Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase | Eur J Endocrinol. 2017 Aug; 177(2): 175–186 | Leiter SM, Parker VER, Welters A, Knox R, Rocha N, Clark G et al. | 2017-08-01 | |
| Metabolic | Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery | Sci Rep. 2017 Aug 21;7(1):9007 | Camastra S, Vitali A, Anselmino M, Gastaldelli A, Bellini R, Berta R et al. | 2017-08-21 | |
| Metabolic | Plasma mannose levels are associated with incident type 2 diabetes and cardiovascular disease | Cell Metab. 2017 Aug 1;26(2):281-283 | Mardinoglu A, Stančáková A, Lotta LA, Kuusisto J, Boren J, Blüher M et al. | 2017-07-09 | |
| Metabolic | Improving economics of NASH/NAFLD treatment through the use of systems biology | Drug Discov Today. 2017 Oct;22(10):1532-1538 | Bosley J, Boren C, Lee S, Grøtli M, Nielsen J, Boren J et al. | 2017-07-09 | |
| Metabolic | Constitutive activation of AKT2 in humans leads to hypoglycemia without fatty liver or metabolic dyslipidemia | J Clin Endocrinol Metab. 2017 Aug 1;102(8):2914-2921 | Minic M, Rocha N, Harris J, Groeneveld MP, Leiter S, Wareham N et al. | 2017-05-23 | |
| Metabolic | Insulin resistance and normal thyroid hormone levels: prospective study and metabolomic analysis | Am J Physiol Endocrinol Metab. 2017 May 1;312(5):E429-E436 | Ferrannini E, Iervasi G, Cobb J, Ndreu R, Nannipieri M | 2017-05-15 | |
| Metabolic | Longitudinal analyses of the steroid metabolome in obese PCOS girls with weight loss. | Endocr Connect. 2017 May;6(4):213-224 | Reinehr T, Kulle A, Rothermel J, Knop-Schmenn C, Lass N, Bosse C, Holterhus PM | 2017-04-03 | |
| AD | The frequency and influence of dementia risk factors in prodromal Alzheimer's disease | Neurobiol Aging. 2017 Aug;56:33-40 | Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W et al. | 2017-08-01 | |
| AD | Does genetic risk help to predict amyloid burden in a non-demented population? A Bayesian approach | bioRxiv doi.org/10.1101/174995 | Voyle N, Jansen W, Keohane A, Patel H, Folarin A, Newhouse S et al. | 2017-08-01 | |
| AD | Strategic roadmap for an early diagnosis of Alzheimer’s disease based on biomarkers | Lancet Neurol. 2017 Aug;16(8):661-676 | Frisoni GB, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K et al. | 2017-08-01 | |
| AD | Amyloid-independent atrophy patterns predict time to progression to dementia in MCI | Alzheimers Res Ther. 2017 Sep 12;9(1):73 | Ten Kate M, Barkhof F, Visser PJ, Teunissen CE, Scheltens P, van der Flier WM, Tijms BM | 2017-09-12 | |
| AD | Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline | Alzheimers Res Ther. 2017 Dec 29;9(1):101 | Bos I, Verhey FR, Ramakers IHGB, Jacobs HIL, Soininen H, Freund-Levi Y et al. | 2017-12-29 | |
| AD | Clinical validity of medial temporal atrophy as a biomarker for Alzheimer’s disease in the context of a structured 5-phase development framework | Neurobiol Aging. 2017 Apr;52:167-182.e1 | Ten Kate M, Barkhof F, Boccardi M, Visser PJ, Jack CR Jr, Lovblad KO et al. | 2017-04-01 | |
| AD | Cognitive functioning of individuals aged 90 years and older withoutdementia: A systematic review | Ageing Res Rev. 2017 Jul;36:42-49 | Legdeur N, Binnekade TT, Otten RH, Badissi M, Scheltens P, Visser PJ, Maier AB | 2017-03-08 | |
| AD | Brain Amyloid Pathology and Cognitive Function - Alzheimer Disease Without Dementia? | JAMA. 2017;317(22):2285-2287 | Visser PJ, Tijms B | 2017-03-01 | |
| AD | Association of blood lipids with Alzheimer’s Disease: a comprehensive lipidomics analysis | Alzheimers Dement. 2017 Feb;13(2):140-151 | Proitsi P, Kim M, Whiley L, Simmons A, Sattlecker M, Velayudhan L et al. | 2017-02-13 | |
| Platform | Real world big data for clinical research and drug development | Drug Discov Today. 2018 Mar;23(3):652-660 | Singh G, Schulthess D, Hughes N, Vannieuwenhuyse B, Kalra D | 2017-12-30 | |
| Platform | La Reutilización de la Información de la Historia Clínica Electrónica para la Investigación. De la Medicina Traslacional a la Medicina de Precisión: el nuevo paradigma "Learning Health System","I+S: Revista de la Sociedad Española de Informática y Salud | 2017 | 124:14-19" | Mayer MA. | 2017-09-01 |
| Platform | General guidelines for biomedical software development | F1000Research 2017, 6:273 | Silva LB, Jimenez RC, Blomberg N, Luis Oliveira J. | 2017-07-12 | |
| Platform | Data Integration and Sharing Supporting Drug R&D | Comprehensive Medicinal Chemistry III vol. 1, pp. 436–443 | Sanz F | 2017-06-13 | |
| Platform | The launch of the European Institute for innovation through health data. | Journal of Medicines Development Sciences, 3(1): 165. | Kalra D, Sundgren M, Claerhout B, et al | 2017-04-01 | |
| Platform | Using Electronic Health Records to Assess Depression and Cancer Comorbidities | Stud Health Technol Inform. 2017;235:236-240 | Mayer MA, Gutierrez-Sacristan A, Leis A, De La Peña S, Sanz F, Furlong LI | 2017-05-01 | |
| Platform | Nine Princples of Semantic Harmonization | AMIA Annu Symp Proc. 2016; 2016: 451–459 | Cunningham JA, Van Speybroeck M, Kalra D, Verbeeck R | 2017-02-10 | |
| Metabolic | Cephalic phase of insulin secretion in response to a meal is unrelated to family history of Type 2 diabetes | PLoS One. 2017 Mar 13;12(3):e0173654 | Eliasson B, Rawshani A, Axelsen M, Hammarstedt A, Smith U. | 2017-03-13 | |
| Metabolic | Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans | Thromb Haemost. 2017 Jan 26;117(2):286-294 | Lallukka S, Luukkonen PK, Zhou Y, Isokuortti E, Leivonen M, Juuti A et al. | 2017-01-26 | |
| AD | Mitochondrial genes are altered in blood early in Alzheimer's disease | Neurobiol Aging. 2017 May;53:36-47 | Lunnon K, Keohane A, Pidsley R, Newhouse S, Riddoch-Contreras J, Thubron EB et al. | 2017-08-01 | |
| AD | The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. | Neurobiol Aging. 2017 Aug;56:33-40 | Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W et al. | 2017-08-01 | |
| Metabolic | Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity | Mol Metab. 2017 Jan; 6(1): 86–100 | Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R et al. | 2017-01-01 | |
| AD | Functional and effective whole brain connectivity using magnetoencephalography to identify monozygotic twin pairs | Sci Rep. 2017 Aug 29;7(1):9685 | Demuru M, Gouw AA, Hillebrand A, Stam CJ, van Dijk BW, Scheltens P et al. | 2017-01-01 |
2016
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE |
|---|---|---|---|---|---|
| Metabolic | Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance | Cell Metab. 2016 Jul 12;24(1):172-84 | Lee S, Zhang C, Kilicarslan M, Piening BD, Bjornson E, Hallström BM et al. | 2016-07-12 |
| AD | Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer's Disease | J Alzheimers Dis. 2017;55(2):813-822 | Lewczuk P, Matzen A, Blennow K, Parnetti L, Molinuevo JL, Eusebi P, Kornhuber J, Morris JC, Fagan AM | 2016-11-01 |
| AD | Complement Biomarkers as predictors of disease progression in Alzheimer’s disease | J Alzheimers Dis. 2016 Sep 6;54(2):707-16 | Hakobyan S, Harding K, Aiyaz M, Hye A, Dobson R, Baird A, Liu B, Harris CL, Lovestone S, Morgan BP | 2016-09-06 |
| Platform | Identificare i casi di diabete tipo 2 in una rete di fonti di dati eterogenee la strategia del progetto EMIF | Not Ist Super Sanità 2016;29(10) | Roberto G, Gini R | 2016-10-01 |
| Metabolic | A systematic review of aetiological and predictive biomarkers of the risk of developing type 2 diabetes | PLoS One. 2016 Oct 27;11(10):e0163721 | Abbasi A, Sahlqvist AS, Lotta L, Brosnan JM, Vollenweider P, Giabbanelli P et al. | 2016-10-27 |
| Metabolic | Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations | JCI Insight. 2016 Oct 20;1(17):e88766 | Huang-Doran I, Tomlinson P, Payne F, Gast A, Sleigh A, Bottomley W et al. | 2016-10-20 |
| AD | Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer’s Disease: Analytical and Diagnostic Characterization | J Alzheimers Dis. 2017;55(1):159-170 | Lewczuk P, Lelental N, Lachmann I, Holzer M, Flach K, Brandner S et al. | 2016-11-01 |
| Platform | Big Data Technologies in Healthcare – Needs, opportunities and challenges | BDVA Valencia Summit White paper | TF7 Healthcare Subgroup. Big Data Value Association | 2016-11-29 |
| Metabolic | Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis | PLoS Med. 2016 Nov 29;13(11):e1002179 | Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin et al. | 2016-11-29 |
| AD | Genetic risk and plasma tau as markers of amyloid-beta and tau burden in cerebrospinal fluid | J Alzheimers Dis. 2017; 55(4): 1417–1427 | Voyle, N, Patel H, Folarin A, Newhouse S, Johnston C, Visser PJ et al. | 2016-12-20 |
| Metabolic | Non-alcoholic fatty liver disease and risk of type 2 diabetes | Best Pract Res Clin Endocrinol Metab. 2016 Jun;30(3):385-95 | Lallukka S, Yki-Järvinen H | 2016-06-01 |
| Platform | Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project | PLoS ONE 11(8): e0160648. | Roberto G, Leal I, Sattar N, Loomis AK, Avillach P, Egger P, et al. | 2016-08-31 |
| Metabolic | Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease | J Hepatol. 2016 May;64(5):1167-75 | Luukkonen PK, Zhou Y, Sädevirta S, Leivonen M, Arola J, Orešič M, Hyötyläinen T, Yki-Järvinen H | 2016-05-01 |
| Metabolic | Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD | Sci Rep. 2016 Apr 19;6:24740 | Petäjä EM, Zhou Y, Havana M, Hakkarainen A, Lundbom N, Ihalainen J, Yki-Järvinen H | 2016-04-19 |
| Platform | Data Safe Havens and Trust: Toward a Common Understanding of Trusted Research Platforms for Governing Secure and Ethical Health Research | JMIR Med Inform. 2016 Jun 21;4(2):e22 | Lea NC, Nicholls J, Dobbs C, Sethi N, Cunningham J, Ainsworth J, Heaven M, Peacock T, Peacock A, Jones K, Laurie G, Kalra D | 2016-06-21 |
| AD | Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond | Lancet Neurol. 2016 Jul;15(8):857-68 | Cuyvers E, Sleegers K | 2016-07-15 |
| AD | A Decade of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Belgium | J Alzheimers Dis. 2016 Aug 10;54(1):383-95. | Somers C, Struyfs H, Goossens J, Niemantsverdriet E, Luyckx J, De Roeck N, De Roeck E, De Vil B, Cras P, Martin JJ, De Deyn PP, Bjerke M, Engelborghs S | 2016-08-10 |
| AD | Validation of microRNAs in Cerebrospinal Fluid as Biomarkers for Different Forms of Dementia in a Multicenter Study | J Alzheimers Dis. 2016 Apr 16;52(4):1321-33. | Müller M, Kuiperij HB, Versleijen AA, Chiasserini D, Farotti L, Baschieri F, Parnetti L, Struyfs H, De Roeck N, Luyckx J, Engelborghs S, Claassen JA, Verbeek MM | 2016-05-08 |
| AD | sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. | EMBO Mol Med. 2016 May 2;8(5):466-76 | Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, Traschütz A, Heneka MT, Struyfs H, Engelborghs S, Sleegers K, Van Broeckhoven C, Zetterberg H, Nellgård B, Blennow K, Crispin A, Ewers M, Haass C | 2016-05-02 |
| Metabolic | Risk factors for spontaneously self-reported postprandial hypoglycemia after bariatric surgery | J Clin Endocrinol Metab. 2016 Oct;101(10):3600-3607 | Nannipieri M, Belligoli A, Guarino D, Busetto L, Moriconi D, Fabris R, Mari A, Baldi S, Anselmino M, Foletto M, Vettor R, Ferrannini E | 2016-06-23 |
| Metabolic | Adipose and circulating CCL18 levels associate with metabolic risk factors in women | J Clin Endocrinol Metab. 2016 Jul 26:jc20162390 | Eriksson Hogling D, Petrus P, Gao H, Bäckdahl J, Dahlman I, Laurencikiene J, Acosta J, Ehrlund A, Näslund E, Kulyte A, Mejhert N, Andersson DP, Arner P, Rydén M | 2016-07-26 |
| Metabolic | The epigenetic signature of systemic insulin resistance in obese women | Diabetologia. 2016 Nov;59(11):2393-405 | Arner P, Sahlqvist AS, Sinha I, Xu H, Yao X, Waterworth D, Rajpal D, Loomis AK, Freudenberg JM, Johnson T, Thorell A, Näslund E, Ryden M, Dahlman I | 2016-08-18 |
| AD | Gray matter network disruptions and amyloid beta in cognitively normal adults | Neurobiol Aging. 2016 Jan;37:154-60 | Tijms BM, Kate MT, Wink AM, Visser PJ, Ecay M, Clerigue M, Estanga A, Garcia Sebastian M, Izagirre A, Villanua J, Martinez Lage P, van der Flier WM, Scheltens P, Sanz Arigita E, Barkhof F | 2016-01-01 |
| AD | Diagnostic Impact of Cerebrospinal Fluid Biomarker (Pre-)Analytical Variability in Alzheimer's Disease | J Alzheimers Dis. 2016;51(1):97-106 | Niemantsverdriet E, Goossens J, Struyfs H, Martin JJ, Goeman J, De Deyn PP, Vanderstichele H, Engelborghs S | 2016-02-01 |
 | AD | Impact of APOE-e4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults | Neurobiol Aging 2016 Feb;38:14-20 | Ten Kate M, Sanz-Arigita EJ, Tijms BM, Wink AM, Clerique M, Garcia-Sebastian M, Izagirre A, Ecay-Torres M, Estanga A, Villanua J, Vrenken H, Visser PJ, Martinez-Lage P, Barkhof F | 2016-02-01 |
| Platform | Semantic Knowledge Base Construction from Radiology Reports | Healthinf, (Biostec 2016) ISBN 978-989-758-170-0, pages 345-352 | Monteiro E, Sernadela P, Matos S, Costa C, Oliveira JL | 2016-02-20 |
| AD | Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics | J Alzheimers Dis. 2016 Mar 1;52(1):51-64 | Lelental N, Brandner S, Kofanova O, Blennow K, Zetterberg H, Andreasson U et al. | 2016-03-01 |
2015
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE |
|---|---|---|---|---|---|
| Platform | PsyGeNET: a knowledge platform on psychiatric disorders and their genes | Bioinformatics. 2015 Sep 15;31(18):3075-7 | Gutiérrez-Sacristán A, Grosdidier S, Valverde O, Torrens M, Bravo À, Piñero J, Sanz F, Furlong LI | 2015-09-15 |
| AD | Alzheimer's disease - Recent biomarker developments in relation to updated diagnostic criteria | Clin Chim Acta 2015 Sep 20;449:3-8 | Höglund K, Fourier A, Perret-Liaudet A, Zetterberg H, Blennow K, Portelius E | 2015-09-20 |
| AD | Validation of the Erlangen Score Algorithm for the prediction of the development of dementia due to AD in pre-dementia subjects | J Alzheimers Dis. 2015 Sep 9;48(2):433-41 | Lewczuk P, Kornhuber J, Toledo JB, Trojanowski JQ, Knapik-Czajka M, Peters O, Wiltfang J, Shaw LM | 2015-09-09 |
| AD | Age-stratified prevalence of mild cognitive impairment and dementia in European populations, a systematic review | J Alzheimers Dis. 2015 Sep 9;48(2):355-9 | Alexander M, Perera G, Ford L, Arrighi HM, Foskett N, Debove C, Novak G, Gordon MF | 2015-09-09 |
| AD | A novel multi-tissue diagnostic of healthy ageing can determine cognitive health status using blood RNA | Genome Biol. 2015; 16(1): 185 | Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJC, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA | 2015-09-07 |
| AD | Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform | Alzheimers Dement. 2015 Sep;11(9):1121-2 | Vaudano E, Vannieuwenhuyse B, Van Der Geyten S, van der Lei J, Visser PJ, Streffer J, Ritchie C, McHale D, Lovestone S, Hofmann-Apitius M,Truyen L, Goldman M | 2015-09-01 |
| AD | No evidence to suggest that the use of acetylcholinesterase inhibitors confounds the results of two blood-based biomarker studies in Alzheimer’s disease | J Alzheimers Dis. 2015 Aug 3;47(3):741-50 | Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M,Vellas B, Hodges A, Lovestone S, Newhouse S, Dobson RJ, Kiddle SJ, Sattlecker M | 2015-08-03 |
| AD | Biomarkers for Alzheimer's disease: a controversial topic | Lancet Neurol. 2015 Aug;14(8):781-3 | Frisoni GB, Visser PJ | 2015-08-01 |
| AD | Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease. | J Alzheimers Dis. 2015;44(1):79-92 | Hall A, Muñoz-Ruiz M, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjonen J, Soininen H;Alzheimer Disease Neuroimaging Initiative; AddNeuroMed consortium; DESCRIPA and Kuopio L-MCI. | 2015-07-07 |
| AD | Blood protein markers of Neocortical Amyloid Burden: A candidate study using SOMAscan technology | J Alzheimers Dis. 2015 Jun 26;46(4):947 | Voyle N, Baker D, Burnham SC, Covin A, Zhang Z, Sangurdekar DP, Tan Hehir CA, Bazenet C, Lovestone S, Kiddle S, Dobson RJ | 2015-07-01 |
| AD | Cerebrospinal fluid P-tau181P: biomarker for improved differential diagnosis | Front Neurol. 2015 Jun 17;6:138 | Struyfs H, Niemantsverdriet E, Goossens J, Fransen E, Martin JJ, De Deyn PP, Engelborghs S | 2015-06-17 |
| AD | Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes | Transl Psychiatry. 2015 Jun 16;5:e584 | Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S,Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ | 2015-06-16 |
| Metabolic | Associations between potentially modifiable risk factors and Alzheimer’s disease: A Mendelian randomization study | PLoS Med. 2015 Jun 16;12(6):e1001841 | Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE; Alzheimer’s Disease Genetics Consortium; GERAD1 Consortium; EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA | 2015-06-09 |
| AD | Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis | JAMA. 2015 May 19; 313(19): 1924–1938 | Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FRJ, Visser PJ, and the Amyloid Biomarker Study Group | 2015-05-19 |
| AD | Temporal evolution of biomarkers and cognitive markers in the asymptomatic, MCI, and dementia stage of Alzheimer's disease | Alzheimers Dement. 2015 May;11(5):511-22 | Bertens D, Knol DL, Scheltens P, Visser PJ; Alzheimer's Disease Neuroimaging Initiative | 2015-05-01 |
| AD | Importance and impact of pre-analytical variables on Alzheimer’s disease biomarker levels in cerebrospinal fluid | Clin Chem Apr 2015; 61(5):734-743 | Le Bastard N, De Deyn PP, Engelborghs S | 2015-04-13 |
| AD | Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage | Brain. 2015 May;138(Pt 5):1327-38 | Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Muscio C, Herukka SK, Salmon E,Bastin C, Wallin A, Nordlund A, de Mendonça A, Silva D, Santana I, Lemos R, Engelborghs S, Van der Mussele S; Alzheimer’s Disease Neuroimaging Initiative, Freund-Levi Y, Wallin ÅK, Hampel H, van der Flier W, Scheltens P, Visser PJ | 2015-02-18 |
| Metabolic | Adipose Tissue Morphology Predicts Improved Insulin Sensitivity Following Moderate Weight Loss | Int J Obes (Lond). 2015 Jun;39(6):893-8 | Eriksson-Hogling D, Andersson DP, Bäckdahl J, Hoffstedt J, Rössner S, Thorell A, Arner E, Arner P, Rydén M | 2015-02-10 |
| AD | Linking genetics of brain changes to Alzheimer’s disease: sparse whole genome association scan of regional MRI volumes in the ADNI and AddNeuroMed cohorts | J Alzheimers Dis. 2015;45(3):851-64 | Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Dobson R,Simmons A; AddNeuroMed consortium; Alzheimer's Disease Neuroimaging Initiative | 2015-02-03 |
| AD | An Integrated Workflow for Multiplex CSF Proteomics and Peptidomics-Identification of Candidate Cerebrospinal Fluid Biomarkers of Alzheimer's Disease | J Proteome Res. 2015 Feb 6;14(2):654-63 | Hölttä M, Minthon L, Hansson O, Holmén-Larsson J, Pike I, Ward M, Kuhn K, Rüetschi U, Zetterberg H, Blennow K, Gobom J | 2015-02-01 |
| AD | TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies | Acta Neuropathol Commun. 2015 Apr 1;3:15 | Goossens J, Vanmechelen E, Trojanowski JQ, Lee VM, Van Broeckhoven C, van der Zee J, Engelborghs S | 2015-02-01 |
| AD | Overdiagnosing vascular dementia using structural brain imaging for dementia work-up | J Alzheimers Dis. 2015;45(4):1039-43 | Niemantsverdriet E, Feyen BF, Le Bastard N, Martin JJ, Goeman J, De Deyn PP, Engelborghs S | 2015-01-15 |
| AD | Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease | Transl Psychiatry. 2015 Jan 13;5:e494 | Proitsi P, Kim M, Whiley L, Pritchard M, Leung R, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Sham P, Lovestone S, Powell JF,Dobson RJ, Legido-Quigley C | 2015-01-13 |
| AD | Diagnostic accuracy of CSF amyloid-β isoforms for early and differential dementia diagnosis | J Alzheimers Dis. 2015;45(3):813-22 | Struyfs H, Van Broeck B, Timmers M, Fransen E, Sleegers K, Van Broeckhoven C, De Deyn PP, Streffer JR, Mercken M, Engelborghs S | 2015-01-01 |
| Platform | Reuse of EHRs to Support Clinical Research in a Hospital of Reference | Stud Health Technol Inform. 2015;210:224-6 | Mayer MA, Furlong LI, Torre P, Planas I, Cots F, Izquierdo E, Portabella J, Rovira J, Gutierrez-Sacristan A, Sanz F | 2015-01-01 |
| AD | Blood protein predictors of brain amyloid for enrichment in clinical trials? | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 1 (2015) 48–60 | Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wonga KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, Covini A, Tan Hehir C, Baker D, Bazenet C, Lovestone S, on behalf of the AIBL Research Group | 2015-03-01 |
| Metabolic | Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2 | J Hepatol 2015 Mar; 62(3):657-63 | Zhou Y, Llauradó G, Oresic M, Hyötyläinen T, Orho-Melander M, Yki-Järvinen H | 2015-03-01 |
| AD | Longitudinal protein changes in blood plasma associated with the rate of cognitive decline in Alzheimer's disease | J Alzheimers Dis. 2015;49(4):1105-14 | Sattlecker M, Khondoker M, Proitsi P, Williams S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Dobson RJ | 2015-11-23 |
| Metabolic | Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance | Sci Rep 2015 Dec 17;5:18366 | Yew Tan C, Virtue S, Murfitt S, Robert LD, Phua YH, Dale M, Griffin JL, Tinahones F, Scherer PE, Vidal-Puig A | 2015-12-17 |
| Metabolic | Body mass index and risk of non-alcoholic fatty liver disease: Two electronic health record prospective studies | J Clin Endocrinol Metab 2016 Mar;101(3):945-52 | Loomis AK, Kabadi S, Preiss D, Hyde C, Bonato V, St Louis M, Desai J, Gill JM, Welsh P, Waterworth D, Sattar N | 2015-12-16 |
| Metabolic | Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI categories: A Systematic Review and Network Meta-Analysis | Diabetes Care 2015 Nov;38(11):2177-87 | Lotta LA, Abbasi A, Sharp SJ, Sahlqvsit AS, Waterworth D, Brosnan JM, Scott RA, Langenberg C, Wareham NJ | 2015-11-01 |
| Metabolic | Evidence of a causal association between hyperinsulinaemia and endometrial cancer: A Mendelian randomization analysis | J Natl Cancer Inst 2015 Jul 1;107(9): pii: djv178 | Nead KT, Sharp SJ, Thompson DJ, Painter JN, Savage DB, Semple RK, Barker A, Australian National Endometrial Cancer Study Group (ANECS), Perry JR, Attia J, Dunning AM, Easton DF, Holliday E, Lott LA, O'Mara T, McEvoy M, Pharoah PD, Scott RJ, Spurdle AB, Langenberg C, Wareham NJ, Scott RA | 2015-07-01 |
| AD | Alzheimer's disease: a report from the 7th Kuopio Azheimer symposium | Neurodegener Dis Manag 2015 Oct;5(5):379-82 | Haapasalo A, Pikkarainen M, Soininen H | 2015-10-29 |
| AD | A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis | J Alzheimers Dis 2015 Oct 15;49(3):659-69 | Voyle N, Keohane A, Newhouse S, Lunnon K, Johnston C, Soininen H Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, Kiddle S, Dobson RJ | 2015-10-15 |
| Metabolic | Type 2 diabetes in migrant South Asians: mechanisms, mitigation and management | Lancet Diabetes Endocrinol 2015 Dec;3(12):1004-16 | Sattar N, Gill JM | 2015-12-01 |
| Metabolic | Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue | Sci Rep 2015 Oct 5;5:14841 | Mardinoglu A, Heiker JT, Gärtner D, Björnson E, Schön MR, Flehmig G, Klöting N, Krohn K, Fasshauer M, Stumvoll M, Nielsen J, Blüher M | 2015-10-05 |
| Platform | Challenges and opportunities for exploring patient-level data | Biomed Res Int 2015;2015:150435 | Lopes P, Bastião Silva L, Oliveira JL | 2015-10-04 |
| Metabolic | The UK10K project identifies rare variants in health and disease | Nature 2015 Oct 1;526(7571):82-90 | UK10K Consortium, Walter K, Min JL, Huang J, Crooks L, Memari Y, McCarthy S, Perry JR, Xu C, Futema M, Lawson D, Iotchkova V, Schiffels S, Hendricks AE, Danecek P, Li R, Floyd J, Wain LV, Barroso I, Humphries SE, Hurles ME, Zeggini E, Barrett JC, Plagnol V, Richards JB, Greenwood CM, Timpson NJ, Durbin R, Soranzo N | 2015-10-01 |
| AD | The genetic landscape of Alzheimer's disease: clinical implications and perspectives | Genet Med 2015 Aug 27 | Van Cauwenberghe C, Van Broeckhoven C, Sleegers K | 2015-08-27 |
| Metabolic | The epigenetic signature of subcutaneous fat is linked to altered expression of genes implicated in lipid metabolism in obese women | Clin Epigenetics 2015 Sep 8;7(1):93 | Arner P, Sinha I, Thorell A, Rydén M, Dahlman-Wright K, Dahlman I | 2015-09-08 |
| Metabolic | Tyrosine is associated with insulin resistance in longitudinal metabolomic profiling of obese children | J Diabetes Res 2016;2016 | Hellmuth C, Kirchberg FF, Lass N, Harder U, Peissner W, Koletzko B, Reinehr T | 2015-09-06 |
| AD | Current developments in dementia risk prediction modelling: An updated systematic review | PLoS One 2015 Sep 3;10(9):2136181 | Tang EY, Harrison SL, Errington L, Gordon MF, Visser PJ, Novak G, Dufouil C, Brayne C, Robinson L, Launer LJ, Stephan BC | 2015-09-03 |
| Platform | Café Variome: General-Purpose Software for Making Genotype-Phenotype Data Discoverable in Restricted or Open Access Contexts | Hum Mutat 2015 Oct;36(10):957-64 | Lancaster O, Beck T, Atlan D, Swertz M, Thangavelu D, Veal C, Dalgleish R, Brookes AJ | 2015-08-25 |
| Platform | Architecture to summarize patient-level data across borders and countries | Stud Health Technol Inform 2015;216:687-90 | Bastião Silva LA, Días C, van der Lei J, Oliveira JL | 2015-08-19 |
| AD | Blood metabolite markers of neocortical amyloid-β burden: Discovery and enrichment using candidate proteins | Transl Psychiatry 2016 Jan 26;6:e719 | Voyle N, Kim M, Proitsi P, Ashton NJ, Baird AL, Bazenet C, Hye A, Westwood S, Chung R, Ward M, Rabinovici GD, Lovestone S, Breen G, Legido-Quigley C, Dobson RJ, Kiddle SJ | 2015-08-18 |
| AD | C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease | Alzheimers Dement 2015 Dec;11(12):1461-9 | De Vos A, Jacobs D, Struyfs H, Fransen E, Andersson K, Portelius E, Andreasson U, De Surgeloose D, Hernalsteen D, Sleegers K, Robberecht C, Van Broeckhoven C, Zetterberg H, Blennow K, Engelborghs S, Vanmechelen E | 2015-12-01 |
| AD | Prevalence of Amyloid PET Positivity in Dementia Syndromes: A Meta-Analysis | JAMA 2015 May 19;313(19):1939-49 | Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ, Amyloid PET Study Group, Verfaillie SC, Zwan MD, Adriaanse SM, Lammertsma AA, Barkhof F, Jaqust WJ, Miller BL, Rosen HJ, Landau SM, Villemagne VL, Rowe CC, Lee DY, Na DL, Seo SW, Sarazin M Roe CM, Sabri O, Barthel H, Koglin N, Hodges J, Leyton CE, Vandenberghe R, van Laere K, Drzezga A, Forster S, Grimmer T, Sánchez-Juan P, Carril JM, Mok V, Camus V, Klunk WE, Cohen AD, Meyer PT, Hellwig S, Newberg A, Frederiksen KS, Fleisher AS, Mintun MA, Wolk DA, Nordberg A, Rinne JO, Chételat G, Lleo A, Blesa R, Fortea J, Madasen K, Rodrigue KM, Brooks DJ | 2015-05-19 |
| Metabolic | The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes | Int J Obes (Lond) 2015 Jun;39(6):910-9 | Dahlman I, Sinha I, Gao H, Brodin D, Thorell A, Rydén M, Andersson DO, Henriksson J, Perfilyev A, Ling C, Dahlman-Wright K, Arner P | 2015-03-18 |
| AD | Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects | Brain 2015 Sep;138(Pt9):2701-15 | Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, Moghekar A, Albert M, Hu WT, Monge Argilés JA, Gorostidi A, Teunissen CE, De Deyn PP, Hyman BT, Molinuevo JL, Frisoni GB, Linazasoro G, de Leon MJ, van der Flier WM, Scheltens O, Blennow K, Shaw LM, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative | 2015-07-28 |
| AD | Diffusion kurtosis imaging: a biomarker for early diagnosis of Alzheimer’s disease? | J Alzheimers Dis. 2015; 48(4):937-48 | Struyfs H, Van Hecke W, Veraart J, Sijbers J, Slaets S, De Belder M, Wuyts L, Peters B, Sleegers K, Robberecht C, Van Broeckhoven C, De Belder F, Parizel PM, Engelborghs S | 2015-10-27 |
2014
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE |
|---|---|---|---|---|---|
| AD | A 22-SNP Alzheimer risk score correlates with family history, onset age and CSF Aβ42 | Alzheimers Dement. 2015 Jun 15. pii: S1552-5260(15)00191-0 | Sleegers, Bettens, De Roeck, Van Cauwenberghe, Cuyvers, Verheijen J, Struyfs H, Van Dongen J, Vermeulen S, Engelborghs S,Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C; BELNEU consortium | 2014-12-26 |
| AD | Diagnostic value of MIBG cardiac scintigraphy for differential dementia diagnosis | Int J Geriatr Psychiatry. 2015 Aug;30(8):864-9 | Slaets S, Van Acker F, Versijpt J, Hauth L, Goeman J, Martin JJ, De Deyn PP, Engelborghs S | 2014-11-03 |
| Metabolic | Family history of type 2 diabetes increases the risk of both obesity and its complications: is type 2 diabetes a disease of inappropriate lipid storage? | J Intern Med. 2015 May;277(5):540-51 | Cederberg H, Stancáková A, Kuusisto J, Laakso M, Smith U | 2014-01-09 |
| Metabolic | Type 2 diabetes as a disease of ectopic fat? | BMC Med. 2014 Aug 26;12:123 | Sattar N, Gill JM | 2014-08-26 |
| AD | Temporal evolution of biomarkers and cognitive markers in the asymptomatic, MCI, and dementia stage of Alzheimer's disease | Alzheimers Dement. 2015 May;11(5):511-22 | Bertens D, Knol DL, Scheltens P, Visser PJ; Alzheimer's Disease Neuroimaging Initiative | 2014-08-20 |
| AD | Circulating Proteomic Signatures of Chronological Age | J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):809-16 | Menni C, Kiddle SJ, Mangino M, Viñuela A, Psatha M, Steves C, Sattlecker M, Buil A, Newhouse S, Nelson S, Williams S, Voyle N, Soininen H,Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Spector TD, Dobson R, Valdes AM | 2014-08-14 |
| Metabolic | Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance | J Clin Invest. 2014 Sep;124(9):4028-38 | Payne F, Colnaghi R, Rocha N, Seth A, Harris J, Carpenter G, Bottomley WE, Wheeler E, Wong S, Saudek V, Savage D, O'Rahilly S, Carel JC, Barroso I,O'Driscoll M, Semple R | 2014-08-08 |
| AD | Depression in mild cognitive impairment is associated with progression to Alzheimer's disease: a longitudinal study | J Alzheimers Dis. 2014;42(4):1239-50 | Van der Mussele S, Fransen E, Struyfs H, Luyckx J, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, Engelborghs S | 2014-07-07 |
| AD | Plasma proteins predict conversion to dementia from prodromal disease | Alzheimers Dement. 2014 Nov;10(6):799-807 | Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K,Keohane A, Ward M, Pike I, Zucht HD, Pepin D, Zheng W, Tunnicliffe A, Richardson J, Gauthier S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S | 2014-07-03 |
| Metabolic | Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease | Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8901-6 | Payne F, Lim K, Girousse A, Brown RJ, Kory N, Robbins A, Xue Y, Sleigh A, Cochran E, Adams C, Dev Borman A, Russel-Jones D, Gorden P,Semple RK, Saudek V, O'Rahilly S, Walther TC, Barroso I, Savage DB | 2014-06-17 |
| Platform | Egas: a collaborative and interactive document curation platform | Database (Oxford). 2014 Jun 11;2014. pii: bau048 | Campos D, Lourenço J, Matos S, Oliveira JL | 2014-06-11 |
| AD | Validation of the AD-CSF-index in autopsy-confirmed Alzheimer's disease patients and healthy controls | J Alzheimers Dis. 2014;41(3):903-9 | Struyfs H, Molinuevo JL, Martin JJ, De Deyn PP, Engelborghs S | 2014-04-04 |
| Metabolic | Changes in the serum metabolite profile in obese children with weight loss | Eur J Nutr. 2015 Mar;54(2):173-81 | Reinehr T, Wolters B, Knop C, Lass N, Hellmuth C, Harder U, Peissner W, Wahl S, Grallert H, Adamski J, Illig T, Prehn C, Yu Z, Wang-Sattler R, Koletzko B | 2014-04-17 |
| AD, Metabolic | Advanced glycation end products, dementia and diabetes | Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4743-4 | Lovestone S, Smith U | 2014-04-01 |
| Metabolic | A population-based study on the prevalence of NASH using scores validated against liver histology | J Hepatol. 2014 Apr;60(4):839-46 | Hyysalo J, Männistö VT, Zhou Y, Arola J, Kärjä V, Leivonen M, Juuti A, Jaser N, Lallukka S, Käkelä P, Venesmaa S, Simonen M, Saltevo J, Moilanen L, Korpi-Hyövalti E, Keinänen-Kiukaanniemi S, Oksa H, Orho-Melander M, Valenti L, Fargion S, Pihlajamäki J, Peltonen M, Yki-Järvinen H | 2014-04-01 |
| Metabolic | Circulating Triacylglycerol Signatures in Nonalcoholic Fatty Liver Disease Associated With the I148M Variant in PNPLA3 and With Obesity | Diabetes. 2014 Jan;63(1):312-22 | Hyysalo J, Gopalacharyulu, Bian H, Hyötyläinen T, Leivonen M, Jaser N, Juuti A, Honka MJ, Nuutila P, Olkkonen VM, Oresic M, Yki-Järvinen H | 2014-01-01 |
| Metabolic | Adipose Tissue CIDEA is Associated, Independently of Weight Variation, to Change in Insulin Resistance during a Longitudinal Weight Control Dietary Program in Obese Individuals | PLoS One 2014 Jul; 9(7):e98707 | Monastier E, Déjean S, Le Gall C, Saris WH, Langin D, Viguerie N | 2014-07-01 |
| Platform | Medical imaging archiving: a comparison between several NoSQL solutions | BHI. 2014, Jun;65-68. | LAB Silva, L Beroud, C Costa, JL Oliveira | 2014-06-01 |
| Platform | Normalizing medical imaging archives for dose quality assurance and productivity auditing | MeMeA. 2014, Jun;1-6. | LAB Silva, L Ribeiro, C Costa, JL Oliveira, M Santos | 2014-06-11 |
| Platform | Semantic search over DICOM repositories | 2014 IEEE International Conference on Healthcare Informatics (ICHI). 204, Sept 15-17, p238-246. | LAB Silva, C Costa, JL Oliveira | 2014-09-15 |
2013
| LINK | TOPIC | TITLE | REFERENCE | AUTHOR(S) | DATE |
|---|---|---|---|---|---|
| AD | Unresolved questions in Alzheimer's research - will biomarkers help? | Biomark Med. 2014;8(1):61-3 | Zetterberg H | 2013-12-14 |
| Metabolic | Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids. | Diabetologia. 2013 Oct;56(10):2266-74 | Orešic M, Hyötyläinen T, Kotronen A, Gopalacharyulu P, Nygren H, Arola J, Castillo S, Mattila I, Hakkarainen A, Borra RJ, Honka MJ, Verrijken A, Francque S, Iozzo P, Leivonen M, Jaser N, Juuti A, Sørensen TI, Nuutila P, Van Gaal L, Yki-Järvinen H | 2013-07-04 |
| AD | Preclinical Alzheimer’s disease and its outcome: a longitudinal cohort study | Lancet Neurol. 2013 Oct;12(10):957-65 | Vos SJ, Xiong C, Visser PJ, Jasielec MS, Hassenstab J, Grant EA, Cairns NJ, Morris JC, Holtzman DM, Fagan AM | 2013-01-15 |